Package: ALDEx3 Title: Linear Models for Sequence Count Data Version: 1.3.0 Authors@R: c(person("Justin", "Silverman", email = "JustinSilverman@psu.edu", role = c("aut", "cre")), person("Greg", "Gloor", email = "ggloor@uwo.ca", role = c("aut")), person("Kyle", "McGovern", email = "kvm6065@psu.edu", role = c("aut", "ctb"))) Description: Provides scalable generalized linear and mixed effects models tailored for sequence count data analysis (e.g., analysis of 16S or RNA-seq data). Uses Dirichlet-multinomial sampling to quantify uncertainty in relative abundance or relative expression conditioned on observed count data. Implements scale models as a generalization of normalizations which account for uncertainty in scale (e.g., total abundances) as described in Nixon et al. (2025) and McGovern et al. (2025) . License: MIT + file LICENSE Encoding: UTF-8 Roxygen: list(markdown = TRUE) Suggests: rBeta2009, testthat (>= 3.0.0), lmtest, sandwich, knitr, rmarkdown Config/testthat/edition: 3 Imports: purrr, lme4, lmerTest, reformulas, parallel, MASS, nlme, abind, matrixStats, methods, stats, TMB LinkingTo: TMB, RcppEigen, Matrix Depends: R (>= 3.5) LazyData: true VignetteBuilder: knitr Config/roxygen2/version: 8.0.0 SystemRequirements: C++17 Config/pak/sysreqs: cmake make Repository: https://jsilve24.r-universe.dev Date/Publication: 2026-07-22 19:14:40 UTC RemoteUrl: https://github.com/jsilve24/aldex3 RemoteRef: HEAD RemoteSha: 6ad6e25c8fc9c99227a35d3d71f6e489a6de6106 NeedsCompilation: yes Packaged: 2026-07-24 09:11:05 UTC; root Author: Justin Silverman [aut, cre], Greg Gloor [aut], Kyle McGovern [aut, ctb] Maintainer: Justin Silverman